Detecting Molecular Expression Patterns Within Tissues
Spatial profiling holds great clinical potential for various research, including oncology, immunology, oncoimmunology, neurosciencesand, and cardiology. Spatial profiling provide valuable insight into the differences in the molecular characteristics, reproducibly and rapidly uncover heterogeneity in gene expression patterns within tissue samples. These differences can help to better understand the mechanisms underlying presence of tumor or other cell populations.
This technology also involves the sequencing of hundreds of mRNAs directly in tissue sections while preserving the spatial information of the tissue in order to generate single-cell gene expression maps of hundreds of genes in intact biological sample.