Detecting Molecular Expression Patterns Within Tissues
Spatial profiling, also known as spatial transcriptomics, is a cutting-edge technique that enables the mapping of gene expression patterns within intact tissue sections. Traditional transcriptomic analysis provides information on gene expression levels but lacks spatial context. Spatial profiling overcomes this limitation by preserving the spatial information of gene expression, allowing us to understand the organization and distribution of different cell types and gene expression patterns within a tissue sample.
Recent advancements in sequencing technologies have led to the development of spatially resolved transcriptomic methods. These techniques combine next-generation sequencing with spatial barcoding to obtain high-throughput gene expression data while preserving the spatial information.