Aptamers are RNA or DNA oligonucleotides (or peptides) that, through their 3-dimensional structures, bind to specific target molecules with high affinity and specificity. Aptamers are generated fast and applied in the inhibition, characterization of proteins, and specific detection.
A class of chemical substances used to prevent or reduce coagulation of the blood. Anticoagulant Therapy can prevent formation of dangerous clots that could lead to:
- Atrial fibrillation
- Coronary artery disease
- Deep vein thrombosis (can lead to pulmonary embolism)
- Ischemic stroke
- Hypercoagulable states (e.g., Factor V Leiden) can lead to deep vein thrombosis
- Myocardial infarction
- Restenosis from stents
The use of anticoagulant therapy is determined based on the risk and benefits of anticoagulation. There is a tight balance as the therapy may increase the risk of bleeding in patients if not properly administered.